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Frontline

FRONTLINE Plus Flea and Tick Treatment for Large Dogs Up to 45 to 88 lbs. 3 Treatments 3 Count

4.4
Based on 48,913 reviews
Independent Analysis
No paid placements

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Technical Specifications

Complete product details

Item Weight
0.64 ounces
Department
Insect Control
Manufacturer
Boehringer Ingelheim Animal Health
ASIN
B0002J1FOE
Item model number
72219
Customer Reviews
4.4 4.4 out of 5 stars 48,913 ratings 4.4 out of 5 stars
Date First Available
September 2, 2004
Item Package Dimensions L x W x H
5.83 x 4.38 x 0.75 inches
Item Dimensions LxWxH
5.75 x 0.75 x 4.5 inches
Item Weight
18.14 g
Brand Name
Frontline
Target Audience Keyword
( reptiles | amphibians ), dogs, dogs|( reptiles | amphibians )
Directions
Directions for Use Step 1. To REMOVE Applicator: 1. Use scissors to separate one blister; 2. Use scissors to cut along dotted line; 3. Peel down foil to remove the applicator. Step 2. OPEN Applicator. Hold upright with foil side toward you and snap applicator tip. Step 3. APPLY FRONTLINE Plus. Part the dog’s hair between the shoulder blades. Place the applicator tip just above the skin and squeeze. Apply entire contents of the applicator in a single spot directly onto the dog’s skin. Do not apply on top of the hair coat. Avoid contact with treated area until dry. Do not allow your dog to ingest the product. Do not apply to dogs weighing less than 45 lbs. or younger than 8 weeks of age. Do not use more than one application per dog per month. Frequency Use monthly to control fleas and ticks. Do not reapply FRONTLINE Plus for 30 days.
Country of Origin
France
Warranty Description
only for dog
Model Name
FRONTLINE Plus for Dogs Medium Dog (23-44 pounds) Flea and Tick Treatment, 3 Doses
Color
Purple Box
Size
3 Count
Material
Fipronil, S-Methoprene
Age Range Description
All Life Stages
Care Instructions
Do not use on kittens under 8 weeks of age or 1.5 lbs
Number of Items
1
Style
Large Dog (45-88 lbs.)
Breed Recommendation
Large Dog, 45 to 88 pounds
Included Components
Package includes 3 applicators
Specific Uses for Product
Parasites
Is Discontinued By Manufacturer
No
Product Dimensions
5.75 x 0.75 x 4.5 inches; 0.64 ounces
Manufacturer recommended age
1 month and up
Best Sellers Rank
See Top 100 in Pet Supplies
Brand
Frontline
Item Form
Liquid
Scent
Unscented
Active Ingredients
fipronil and (S)-methoprene
Item Volume
339 Milliliters
Allergen Information
Abalone Free
Age Range (Description)
All Life Stages
UPC
350604287209 666672366389

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About This Review

Researched and written by the Review Atlas editorial team

How We Review This Product

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Our Research Process

  • We analyze the full manufacturer specifications and compare them against competing products
  • We synthesize verified customer feedback to surface recurring praise and complaints
  • We track pricing and availability so recommendations reflect real value at today's prices
  • Manufacturers cannot pay for placement, scores, or favorable coverage
  • Evaluated using our Dog Flea & Tick Control review criteria
Last updated: November 17, 2025
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