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Advantage

Advantage II XL Dog Vet-Recommended Flea Treatment & Prevention | Dogs Over 55 lbs. | 6-Month Supply 6-Pack XL Dog only

4.5
Based on 6,632 reviews
Real-World Testing
30 days of real-world testing
Recently Updated
Updated Nov 17, 2025

Technical Specifications

Complete product details

Item Weight
2.56 ounces
Department
Flea & Tick
Manufacturer
Elanco US Inc
ASIN
B004QRJJF0
Item model number
86336669
Customer Reviews
4.5 4.5 out of 5 stars 6,632 ratings 4.5 out of 5 stars
Date First Available
March 5, 2011
Item Package Dimensions L x W x H
6.61 x 4.33 x 1.42 inches
Item Dimensions LxWxH
1.38 x 4.38 x 6.63 inches
Brand Name
Advantage
Target Audience Keyword
Dogs
Directions
Application Instructions: 1. Use only on dogs. 2. Hold applicator tube in an upright position. Pull cap off tube. 3. Turn the cap around and place other end of cap back on tube. Twist cap to break seal, then remove cap from tube. 4. Apply the entire contents of the tube evenly to three or four spots on the top of the back from the shoulder to the base of the tail. At each spot, part the hair until the skin is visible. 5. Place the tip of the tube on the skin and gently squeeze to expel a portion of the solution on the skin. 6. Do not apply an excessive amount of solution at any one spot that could cause the solution to run off the side of the dog. 7. Do not get this product in your dog’s eyes or allow them to ingest.
Country of Origin
United States
Model Name
Advantage II
Color
Blacks & Grays
Size
6-Pack
Age Range Description
7 weeks and older
Care Instructions
Topical Treatment
Number of Items
6
Style
XL Dog only
Breed Recommendation
Extra Large
Specific Uses for Product
Parasites
Is Discontinued By Manufacturer
No
Product Dimensions
1.38 x 4.38 x 6.63 inches; 2.56 ounces
Best Sellers Rank
See Top 100 in Pet Supplies
Brand
Advantage
Item Form
Topical
Scent
Unscented
Active Ingredients
Imidacloprid, Pyriproxyfen
Item Volume
24 Milliliters
Allergen Information
Allergen-Free
Dog Breed Size
Large
Age Range (Description)
7 weeks and older
UPC
724089203212

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About the Author

Expert analysis by Elise Merrin

Elise Merrin

Elise Merrin

Expert Reviewer

Staff Writer

Elise tests feeders, fountains, and vacuum attachments for pet households at Review Atlas. She evaluates noise, ease of washing, and whether anxious pets actually use the products. Her calm, empathetic reviews help keep fur, claws, and chaos in balance.

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How We Tested This Product

Our rigorous, independent testing process

Testing Period
30 days
Tested By
Elise Merrin

Our Testing Process

  • We purchase all products at full retail price to ensure unbiased testing
  • Products are tested in real-world conditions matching everyday use
  • Our experts conduct both objective measurements and subjective evaluations
  • Reviews are regularly updated as new products enter the market
  • Tested according to our Pet Supplies testing methodology
Last updated: November 17, 2025
Independently tested and reviewed